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Eden Engine

Mouse Gene to Phenotype Associations (IMPC)

impc/gene-phenotype-associations

Statistically significant phenotypes that the International Mouse Phenotyping Consortium found in knockout mice for one mouse gene symbol (for example Akt2, Trp53, Lepr): the Mammalian Phenotype term, top-level system, allele, zygosity, sex, life stage, p-value, effect size, percentage change, measurement and procedure, phenotyping centre and strain. Up to 50 associations per page with paging; numFound gives the total. Gene symbols are case-sensitive. IMPC data, CC BY 4.0, served by Eden Engine; not an official IMPC product.

activeper callv1

Price

$0.0026 per call

You pay the price shown. If a call turns out to cost more than its quote, you pay the actual price, capped at twice the quote. No monthly minimum. Top-ups start at $0.50.

Data source

International Mouse Phenotyping Consortium (IMPC)

Data from the International Mouse Phenotyping Consortium (IMPC, https://www.mousephenotype.org), licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/), served from EMBL-EBI. Served by Eden Engine; not an official IMPC or EMBL-EBI product.

Use it

Five steps: search, inspect, learn, run, settle. No per-tool setup; your agent reaches this tool through the meta-tools it already has.

Connect once and your AI can find and run this tool, and any other it needs.

agent
// 1. search: find the tool
omnial_search({ query: "what you need" })

// 2. inspect: price and input schema
omnial_inspect({ tool: "impc/gene-phenotype-associations" })

// 3. learn: read the usage guide at runtime
omnial_learn({ tool: "impc/gene-phenotype-associations" })

// 4. run: price the exact call first, then run it
omnial_execute({ tool: "impc/gene-phenotype-associations", input: { /* see input_schema */ }, dry_run: true })
omnial_execute({ tool: "impc/gene-phenotype-associations", input: { /* ... */ } })

// 5. settle: the call is charged when it finishes, nothing to do

Not connected yet? Point your MCP client at https://mcp.eden-engine.com/mcp, then copy a config for your client.

Pricing

Every charge this tool can incur.

ChargePrice
Per call
$0.0026
Updated
Oct 25, 2026

Input and output schemas

Input schema
input_schema.json
{
  "type": "object",
  "required": [
    "marker_symbol"
  ],
  "properties": {
    "rows": {
      "type": "integer",
      "default": 25,
      "maximum": 50,
      "minimum": 1,
      "description": "Associations per page, 1 to 50. Defaults to 25."
    },
    "start": {
      "type": "integer",
      "maximum": 100000,
      "minimum": 0,
      "description": "Number of associations to skip for paging. Leave out for the first page."
    },
    "marker_symbol": {
      "type": "string",
      "pattern": "^[A-Za-z0-9._-]{1,30}$",
      "description": "Mouse gene symbol, case-sensitive, for example Akt2, Trp53 or Lepr. A symbol with no significant phenotype (or a wrong-case symbol) returns an empty list."
    }
  },
  "additionalProperties": false
}
Output schema
output_schema.json
{
  "type": "object",
  "required": [
    "response"
  ],
  "properties": {
    "response": {
      "type": "object",
      "required": [
        "numFound",
        "docs"
      ],
      "properties": {
        "docs": {
          "type": "array",
          "items": {
            "type": "object",
            "properties": {
              "sex": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "male, female or not applicable."
              },
              "p_value": {
                "type": [
                  "number",
                  "null"
                ],
                "description": "Statistical significance of the association."
              },
              "zygosity": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "homozygote, heterozygote or hemizygote."
              },
              "mp_term_id": {
                "type": "string",
                "description": "Mammalian Phenotype ontology id, e.g. MP:0002968."
              },
              "effect_size": {
                "type": [
                  "number",
                  "null"
                ],
                "description": "Effect size of the measurement."
              },
              "strain_name": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "mp_term_name": {
                "type": "string"
              },
              "allele_symbol": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "marker_symbol": {
                "type": "string",
                "description": "Mouse gene symbol, case-sensitive, e.g. Akt2."
              },
              "resource_name": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "assertion_type": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "parameter_name": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "procedure_name": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "life_stage_name": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "percentage_change": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "Percentage change versus wild type, as a string as the service sends it."
              },
              "phenotyping_center": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "marker_accession_id": {
                "type": [
                  "string",
                  "null"
                ]
              },
              "top_level_mp_term_name": {
                "type": [
                  "array",
                  "null"
                ],
                "items": {},
                "description": "Top-level phenotype system(s) the term belongs to."
              }
            },
            "additionalProperties": true
          }
        },
        "start": {
          "type": "integer"
        },
        "numFound": {
          "type": "integer",
          "description": "Total matching associations."
        }
      },
      "additionalProperties": true
    },
    "responseHeader": {
      "type": "object",
      "description": "Solr header; `params` echoes the query as built.",
      "additionalProperties": true
    }
  },
  "description": "Solr response: associations in `response.docs`, total in `response.numFound`.",
  "additionalProperties": true
}