Genes Linked to a Mouse Phenotype (IMPC)
impc/phenotype-gene-search
Finds the mouse genes whose knockout produced a given phenotype in International Mouse Phenotyping Consortium screens, by exact Mammalian Phenotype term name (for example abnormal glucose homeostasis, increased body weight, decreased bone mineral density). Each row is one association with gene symbol, term, allele, zygosity, sex, p-value, effect size, measurement, procedure, centre and strain. Up to 50 per page with paging; numFound gives the total. IMPC data, CC BY 4.0, served by Eden Engine; not an official IMPC product.
Price
$0.0026 per call
You pay the price shown. If a call turns out to cost more than its quote, you pay the actual price, capped at twice the quote. No monthly minimum. Top-ups start at $0.50.
Data source
International Mouse Phenotyping Consortium (IMPC)
Data from the International Mouse Phenotyping Consortium (IMPC, https://www.mousephenotype.org), licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/), served from EMBL-EBI. Served by Eden Engine; not an official IMPC or EMBL-EBI product.
Use it
Five steps: search, inspect, learn, run, settle. No per-tool setup; your agent reaches this tool through the meta-tools it already has.
Connect once and your AI can find and run this tool, and any other it needs.
// 1. search: find the tool
omnial_search({ query: "what you need" })
// 2. inspect: price and input schema
omnial_inspect({ tool: "impc/phenotype-gene-search" })
// 3. learn: read the usage guide at runtime
omnial_learn({ tool: "impc/phenotype-gene-search" })
// 4. run: price the exact call first, then run it
omnial_execute({ tool: "impc/phenotype-gene-search", input: { /* see input_schema */ }, dry_run: true })
omnial_execute({ tool: "impc/phenotype-gene-search", input: { /* ... */ } })
// 5. settle: the call is charged when it finishes, nothing to doNot connected yet? Point your MCP client at https://mcp.eden-engine.com/mcp, then copy a config for your client.
Pricing
Every charge this tool can incur.
| Charge | Price |
|---|---|
Per call | $0.0026 |
- Updated
- Oct 25, 2026
Input and output schemas
Input schema
{
"type": "object",
"required": [
"term"
],
"properties": {
"rows": {
"type": "integer",
"default": 25,
"maximum": 50,
"minimum": 1,
"description": "Associations per page, 1 to 50. Defaults to 25."
},
"term": {
"type": "string",
"pattern": "^[A-Za-z0-9 ,'()/+.:-]{2,100}$",
"description": "Exact Mammalian Phenotype term name, for example abnormal glucose homeostasis or increased body weight. Two to 100 characters; letters, digits, spaces and , ' ( ) / + . : - only. A name that is not a term returns an empty list."
},
"start": {
"type": "integer",
"maximum": 100000,
"minimum": 0,
"description": "Number of associations to skip for paging. Leave out for the first page."
}
},
"additionalProperties": false
}Output schema
{
"type": "object",
"required": [
"response"
],
"properties": {
"response": {
"type": "object",
"required": [
"numFound",
"docs"
],
"properties": {
"docs": {
"type": "array",
"items": {
"type": "object",
"properties": {
"sex": {
"type": [
"string",
"null"
],
"description": "male, female or not applicable."
},
"p_value": {
"type": [
"number",
"null"
],
"description": "Statistical significance of the association."
},
"zygosity": {
"type": [
"string",
"null"
],
"description": "homozygote, heterozygote or hemizygote."
},
"mp_term_id": {
"type": "string",
"description": "Mammalian Phenotype ontology id, e.g. MP:0002968."
},
"effect_size": {
"type": [
"number",
"null"
],
"description": "Effect size of the measurement."
},
"strain_name": {
"type": [
"string",
"null"
]
},
"mp_term_name": {
"type": "string"
},
"allele_symbol": {
"type": [
"string",
"null"
]
},
"marker_symbol": {
"type": "string",
"description": "Mouse gene symbol, case-sensitive, e.g. Akt2."
},
"resource_name": {
"type": [
"string",
"null"
]
},
"assertion_type": {
"type": [
"string",
"null"
]
},
"parameter_name": {
"type": [
"string",
"null"
]
},
"procedure_name": {
"type": [
"string",
"null"
]
},
"life_stage_name": {
"type": [
"string",
"null"
]
},
"percentage_change": {
"type": [
"string",
"null"
],
"description": "Percentage change versus wild type, as a string as the service sends it."
},
"phenotyping_center": {
"type": [
"string",
"null"
]
},
"marker_accession_id": {
"type": [
"string",
"null"
]
},
"top_level_mp_term_name": {
"type": [
"array",
"null"
],
"items": {},
"description": "Top-level phenotype system(s) the term belongs to."
}
},
"additionalProperties": true
}
},
"start": {
"type": "integer"
},
"numFound": {
"type": "integer",
"description": "Total matching associations."
}
},
"additionalProperties": true
},
"responseHeader": {
"type": "object",
"description": "Solr header; `params` echoes the query as built.",
"additionalProperties": true
}
},
"description": "Solr response: associations in `response.docs`, total in `response.numFound`.",
"additionalProperties": true
}