InterPro Domains and Families for a Protein: Entries and Positions (UniProt Accession)

interpro/domains-for-protein

The InterPro entries (families, domains, homologous superfamilies, repeats and sites) that a UniProt protein belongs to, each with its accession, name, type, member-database signatures, Gene Ontology terms and the start and end positions of every matching fragment on the protein. Returns the first page, up to page_size entries (default 20, at most 50), with the total count so a cut-short answer is visible. An accession InterPro does not know returns an empty response, not a list. Data from InterPro (EMBL-EBI), CC0 1.0, served by Eden Engine; not an official EMBL-EBI product.

activeper callv1

Price

$0.0026 per call

You pay the price shown. If a call turns out to cost more than its quote, you pay the actual price, capped at twice the quote. No monthly minimum. Top-ups start at $5.

Data source

EMBL-EBI

Data from InterPro, EMBL's European Bioinformatics Institute (EMBL-EBI), released under CC0 1.0 (interpro-documentation.readthedocs.io/en/latest/license.html). Served by Eden Engine; not an official EMBL-EBI product.

Use it

Five steps: search, inspect, learn, run, settle. No per-tool setup; your agent reaches this tool through the meta-tools it already has.

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agent

// 1. search: find the tool
omnial_search({ query: "what you need" })

// 2. inspect: price and input schema
omnial_inspect({ tool: "interpro/domains-for-protein" })

// 3. learn: read the usage guide at runtime
omnial_learn({ tool: "interpro/domains-for-protein" })

// 4. run: price the exact call first, then run it
omnial_execute({ tool: "interpro/domains-for-protein", input: { /* see input_schema */ }, dry_run: true })
omnial_execute({ tool: "interpro/domains-for-protein", input: { /* ... */ } })

// 5. settle: the call is charged when it finishes, nothing to do

Not connected yet? Point your MCP client at https://mcp.eden-engine.com/mcp, then copy a config for your client.

Pricing

Every charge this tool can incur.

Charge	Price
Per call	$0.0026

Updated: Oct 20, 2026

Input and output schemas

Input schema

input_schema.json

{
  "type": "object",
  "required": [
    "accession"
  ],
  "properties": {
    "accession": {
      "type": "string",
      "pattern": "^([OPQ][0-9][A-Z0-9]{3}[0-9]|[A-NR-Z][0-9]([A-Z][A-Z0-9]{2}[0-9]){1,2})$",
      "description": "A UniProt accession in upper case, for example P04637 (human p53) or Q8N158. Not a gene name and not a UniProt entry name such as P53_HUMAN."
    },
    "page_size": {
      "type": "integer",
      "default": 20,
      "maximum": 50,
      "minimum": 1,
      "description": "How many InterPro entries to return, 1 to 50, default 20. Only the first page is reachable: compare `count` in the response with this number to see whether entries were left out."
    }
  },
  "additionalProperties": false
}

Output schema

output_schema.json

{
  "type": "object",
  "required": [
    "count",
    "results"
  ],
  "properties": {
    "next": {
      "type": [
        "string",
        "null"
      ],
      "description": "InterPro's URL for the following page, or null on the last page. Not callable through this tool."
    },
    "count": {
      "type": "integer",
      "description": "Total number of InterPro entries matching the protein, across all pages."
    },
    "results": {
      "type": "array",
      "items": {
        "type": "object",
        "properties": {
          "metadata": {
            "type": "object",
            "description": "The entry: `accession` (IPR...), `name`, `type` (family, domain, homologous_superfamily, ...), `source_database`, `member_databases` (signatures from Pfam, PANTHER, PRINTS and others), `integrated` and `go_terms`.",
            "additionalProperties": true
          },
          "proteins": {
            "type": "array",
            "items": {
              "type": "object",
              "additionalProperties": true
            },
            "description": "This protein, with `entry_protein_locations`: each location lists `fragments` with `start` and `end` residue positions. `accession` is lower case."
          }
        },
        "additionalProperties": true
      },
      "description": "One element per InterPro entry, in the provider's order."
    },
    "previous": {
      "type": [
        "string",
        "null"
      ]
    }
  },
  "description": "InterPro's paged envelope: the total number of matching entries and one page of them.",
  "additionalProperties": true
}