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Eden Engine

IntAct Molecular Interactions Search (PSICQUIC)

psicquic/query-interactions

Searches the IntAct molecular-interaction database (EMBL-EBI, PSICQUIC) and returns up to `maxResults` interactions (1 to 20, default 10) starting at `firstResult`: both interactors with identifiers, aliases and species, the detection method, first author, publications, interaction type, source database, interaction ids and the IntAct MI score. The `query` is a plain gene, protein or id term (brca2, P04637) or a field query such as `identifier:P04637 AND species:9606`; quotes and brackets are not accepted. A query that matches nothing returns an empty list. Interaction data from IntAct (EMBL-EBI), parsed from the MITAB text and served by Eden Engine; not an official EMBL-EBI product.

activeper callv1

Price

$0.0026 per call

You pay the price shown. If a call turns out to cost more than its quote, you pay the actual price, capped at twice the quote. No monthly minimum. Top-ups start at $0.50.

Data source

EMBL-EBI

Interaction data from IntAct (EMBL-EBI) served over PSICQUIC; EMBL-EBI expects attribution (https://www.ebi.ac.uk/about/terms-of-use). Served by Eden Engine; not an official EMBL-EBI or IntAct product.

Use it

Five steps: search, inspect, learn, run, settle. No per-tool setup; your agent reaches this tool through the meta-tools it already has.

Connect once and your AI can find and run this tool, and any other it needs.

agent
// 1. search: find the tool
omnial_search({ query: "what you need" })

// 2. inspect: price and input schema
omnial_inspect({ tool: "psicquic/query-interactions" })

// 3. learn: read the usage guide at runtime
omnial_learn({ tool: "psicquic/query-interactions" })

// 4. run: price the exact call first, then run it
omnial_execute({ tool: "psicquic/query-interactions", input: { /* see input_schema */ }, dry_run: true })
omnial_execute({ tool: "psicquic/query-interactions", input: { /* ... */ } })

// 5. settle: the call is charged when it finishes, nothing to do

Not connected yet? Point your MCP client at https://mcp.eden-engine.com/mcp, then copy a config for your client.

Pricing

Every charge this tool can incur.

ChargePrice
Per call
$0.0026
Updated
Oct 25, 2026

Input and output schemas

Input schema
input_schema.json
{
  "type": "object",
  "required": [
    "query"
  ],
  "properties": {
    "query": {
      "type": "string",
      "pattern": "^[A-Za-z0-9_.:*-]+( [A-Za-z0-9_.:*-]+)*$",
      "maxLength": 100,
      "minLength": 1,
      "description": "Search term or field query: a gene or protein name (brca2), an id (P04637), or fields joined by AND, OR, NOT such as identifier:P04637 AND species:9606. Letters, digits and _ . : * - only, words separated by single spaces; no quotes, brackets or parentheses."
    },
    "maxResults": {
      "type": "integer",
      "default": 10,
      "maximum": 20,
      "minimum": 1,
      "description": "Most interactions to return, 1 to 20. Default 10."
    },
    "firstResult": {
      "type": "integer",
      "default": 0,
      "maximum": 100000,
      "minimum": 0,
      "description": "Zero-based index of the first interaction to return. Default 0."
    }
  },
  "additionalProperties": false
}
Output schema
output_schema.json
{
  "type": "object",
  "required": [
    "interactionCount",
    "interactions"
  ],
  "properties": {
    "interactions": {
      "type": "array",
      "items": {
        "type": "object",
        "required": [
          "interactorA",
          "interactorB",
          "publications",
          "interactionIds",
          "confidence"
        ],
        "properties": {
          "confidence": {
            "type": "array",
            "items": {
              "type": "object",
              "required": [
                "type",
                "value"
              ],
              "properties": {
                "type": {
                  "type": "string",
                  "description": "Score name, for example intact-miscore."
                },
                "value": {
                  "type": [
                    "number",
                    "string"
                  ],
                  "description": "Score value."
                }
              },
              "additionalProperties": true
            },
            "description": "Confidence scores."
          },
          "firstAuthor": {
            "type": [
              "string",
              "null"
            ],
            "description": "First author and year of the publication, for example Formstecher et al. (2005)."
          },
          "interactorA": {
            "type": "object",
            "required": [
              "id",
              "alternativeIds",
              "aliases",
              "taxId",
              "taxName"
            ],
            "properties": {
              "id": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "Primary identifier as db:id, for example uniprotkb:P04637."
              },
              "taxId": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "NCBI taxon id."
              },
              "aliases": {
                "type": "array",
                "items": {
                  "type": "object",
                  "properties": {
                    "name": {
                      "type": "string"
                    },
                    "type": {
                      "type": [
                        "string",
                        "null"
                      ],
                      "description": "Alias kind, for example gene name."
                    }
                  },
                  "additionalProperties": true
                },
                "description": "Names the interactor is known by, at most 8."
              },
              "taxName": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "Scientific name of the taxon."
              },
              "alternativeIds": {
                "type": "array",
                "items": {
                  "type": "string"
                },
                "description": "Other identifiers as db:id, at most 8."
              }
            },
            "additionalProperties": true
          },
          "interactorB": {
            "type": "object",
            "required": [
              "id",
              "alternativeIds",
              "aliases",
              "taxId",
              "taxName"
            ],
            "properties": {
              "id": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "Primary identifier as db:id, for example uniprotkb:P04637."
              },
              "taxId": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "NCBI taxon id."
              },
              "aliases": {
                "type": "array",
                "items": {
                  "type": "object",
                  "properties": {
                    "name": {
                      "type": "string"
                    },
                    "type": {
                      "type": [
                        "string",
                        "null"
                      ],
                      "description": "Alias kind, for example gene name."
                    }
                  },
                  "additionalProperties": true
                },
                "description": "Names the interactor is known by, at most 8."
              },
              "taxName": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "Scientific name of the taxon."
              },
              "alternativeIds": {
                "type": "array",
                "items": {
                  "type": "string"
                },
                "description": "Other identifiers as db:id, at most 8."
              }
            },
            "additionalProperties": true
          },
          "publications": {
            "type": "array",
            "items": {
              "type": "string"
            },
            "description": "Publication ids as db:id (pubmed, imex), at most 8."
          },
          "interactionIds": {
            "type": "array",
            "items": {
              "type": "string"
            },
            "description": "Interaction ids as db:id (intact, imex), at most 8."
          },
          "sourceDatabase": {
            "type": [
              "object",
              "null"
            ],
            "properties": {
              "id": {
                "type": "string"
              },
              "name": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "Term name."
              }
            },
            "description": "Controlled-vocabulary term; null when absent.",
            "additionalProperties": true
          },
          "detectionMethod": {
            "type": [
              "object",
              "null"
            ],
            "properties": {
              "id": {
                "type": "string"
              },
              "name": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "Term name."
              }
            },
            "description": "Controlled-vocabulary term; null when absent.",
            "additionalProperties": true
          },
          "interactionType": {
            "type": [
              "object",
              "null"
            ],
            "properties": {
              "id": {
                "type": "string"
              },
              "name": {
                "type": [
                  "string",
                  "null"
                ],
                "description": "Term name."
              }
            },
            "description": "Controlled-vocabulary term; null when absent.",
            "additionalProperties": true
          }
        },
        "additionalProperties": true
      }
    },
    "interactionCount": {
      "type": "integer",
      "description": "Number of interactions in this answer; 0 when nothing matched."
    }
  },
  "description": "Up to 20 interactions parsed from MITAB 2.5.",
  "additionalProperties": true
}