Reactions Catalysed by an Enzyme EC Number (Rhea)

rhea/reactions-by-ec

Returns the Rhea biochemical reactions catalysed by an enzyme with a given EC number, for example 1.14.13.7, or by every enzyme of an EC class when the trailing parts are the wildcard - (for example 1.14.13.-). Each reaction has its Rhea id (without the RHEA: prefix), plain-text equation, curation status, and balanced and transport flags, in id order, paged with limit and offset. An EC number with no reaction returns an empty list. Up to 100 reactions per call. Rhea data under CC BY 4.0, served by Eden Engine; not an official Rhea or SIB product.

activeper callv2

Price

$0.0026 per call

You pay the price shown. If a call turns out to cost more than its quote, you pay the actual price, capped at twice the quote. No monthly minimum. Top-ups start at $5.

Data source

Rhea

Data from Rhea, the expert-curated biochemical reaction database of the SIB Swiss Institute of Bioinformatics (rhea-db.org), licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/); changes: reaction rows selected from the SPARQL result set and reshaped into flat objects. Credit: Rhea (rhea-db.org). Served by Eden Engine; not an official Rhea or SIB product.

Use it

Five steps: search, inspect, learn, run, settle. No per-tool setup; your agent reaches this tool through the meta-tools it already has.

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agent

// 1. search: find the tool
omnial_search({ query: "what you need" })

// 2. inspect: price and input schema
omnial_inspect({ tool: "rhea/reactions-by-ec" })

// 3. learn: read the usage guide at runtime
omnial_learn({ tool: "rhea/reactions-by-ec" })

// 4. run: price the exact call first, then run it
omnial_execute({ tool: "rhea/reactions-by-ec", input: { /* see input_schema */ }, dry_run: true })
omnial_execute({ tool: "rhea/reactions-by-ec", input: { /* ... */ } })

// 5. settle: the call is charged when it finishes, nothing to do

Not connected yet? Point your MCP client at https://mcp.eden-engine.com/mcp, then copy a config for your client.

Pricing

Every charge this tool can incur.

Charge	Price
Per call	$0.0026

Updated: Oct 21, 2026

Input and output schemas

Input schema

input_schema.json

{
  "type": "object",
  "required": [
    "ec_number",
    "limit"
  ],
  "properties": {
    "limit": {
      "type": "integer",
      "maximum": 100,
      "minimum": 1,
      "description": "Maximum number of reactions to return, 1 to 100. Required: a broad query matches thousands of reactions."
    },
    "offset": {
      "type": "integer",
      "default": 0,
      "minimum": 0,
      "description": "Number of reactions to skip, for paging. Leave out for the first page."
    },
    "ec_number": {
      "type": "string",
      "pattern": "^(?:[0-9]+\\.[0-9]+\\.[0-9]+\\.(?:[0-9]+|-)|[0-9]+\\.[0-9]+\\.-\\.-|[0-9]+\\.-\\.-\\.-)$",
      "maxLength": 20,
      "description": "A four-part Enzyme Commission number, for example 1.14.13.7 (phenol 2-monooxygenase). Trailing parts may be the wildcard -, as in 1.14.13.-, 1.14.-.- or 1.-.-.-, to take every enzyme of that class; a wildcard may not be followed by a number."
    }
  },
  "additionalProperties": false
}

Output schema

output_schema.json

{
  "type": "object",
  "required": [
    "results"
  ],
  "properties": {
    "results": {
      "type": "array",
      "items": {
        "type": "object",
        "required": [
          "id",
          "equation"
        ],
        "properties": {
          "id": {
            "type": "string",
            "description": "Rhea reaction id without the RHEA: prefix, for example 17061."
          },
          "status": {
            "type": "string",
            "description": "Curation status, for example approved."
          },
          "comment": {
            "type": "string",
            "description": "Curator comment, often empty."
          },
          "balanced": {
            "type": "boolean",
            "description": "Whether the reaction is atom- and charge-balanced."
          },
          "equation": {
            "type": "string",
            "description": "Plain-text reaction equation, substrates = products."
          },
          "transport": {
            "type": "boolean",
            "description": "Whether the reaction is a transport reaction."
          },
          "htmlequation": {
            "type": "string",
            "description": "The equation as HTML markup with compound links; escape or sanitise before rendering."
          }
        },
        "additionalProperties": true
      },
      "description": "Rhea reactions, in the order Rhea returns them. Empty when nothing matches."
    }
  },
  "description": "The matching reactions, as a results list (empty when nothing matches).",
  "additionalProperties": true
}